Tn, a carcinoma-associated antigen, reacts with anti-Tn of normal human sera
نویسندگان
چکیده
منابع مشابه
Mucin associated Tn and sialosyl-Tn antigen expression in colorectal polyps.
Sialosyl-Tn antigen and its immediate precursor, Tn antigen, are carbohydrate structures associated with the earliest steps of mucin O-linked glycosylation. Both antigens have been shown previously to be highly sensitive and specific markers of colorectal cancer. One hundred and three colorectal polyps (79 adenomatous; 24 hyperplastic) were examined for expression of Tn antigen using vicia vill...
متن کاملImmunocytological analysis of the Tn associated antigen 83D4 in serous effusions from patients with cancer: comparison with Tn soluble glycoprotein.
AIMS To determine whether the monoclonal antibody (MoAb) 83D4, previously shown to be highly specific for carcinoma cells, can be used as an immunocytological marker to discriminate between benign and malignant cells in serous effusions; and to test for a correlation between expression of the antigen reacting with MoAb 83D4 on effusion cells and the amount of soluble 83D4 antigen in effusion fl...
متن کاملTN staging of gastric carcinoma
Accepted for publication 15 September 1992 Abstract From 1986 to 1990 a prospective comparative study was undertaken to compare the relative accuracy of computed tomography, endogastric ultrasonography, and intraoperative surgical assessment in evaluating the depth of invasion (T category) and involvement of lymph nodes (N category) of patients with gastric carcinoma. One hundred and eight cons...
متن کاملPresence of the Tn antigen on hematopoietic progenitors from patients with the Tn syndrome.
The Tn syndrome is an acquired clonal disorder characterized by the exposure of a normally hidden determinant, the Tn antigen, on the surface of human erythrocytes, platelets, granulocytes, and lymphocytes. Two distinct populations, Tn positive (Tn+) and Tn negative (Tn-), of mature hemopoietic cells are present in Tn patients. To determine whether the Tn antigen is already expressed on erythro...
متن کاملAutoradiographic studies of tn/tn mouse embryos.
High-resolution autoradiographic studies were used to determine whether t12/t12 and tw32/tw32 mouse embryos synthesize the excessive lipid which distinguishes these embryos prior to their death. The studies show that the tn homozygotes synthesize neutral lipid which is stored in intracellular lipid droplets. Cholesterol and phospholipid precursors are not incorporated into these droplets.
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ژورنال
عنوان ژورنال: Cancer
سال: 1985
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19850201)55:3<561::aid-cncr2820550315>3.0.co;2-1